Minimizing Patient-Specific Tracer Dose in Myocardial Perfusion Imaging Using CZT SPECT

What is the minimum product of tracer dose and scan time that will still produce the diagnostic value required for cadmium zinc telluride (CZT) SPECT Myocardial Perfusion Imagining (MPI)?

What is the minimum product of tracer dose and scan time that will still produce the diagnostic value required for cadmium zinc telluride (CZT) SPECT Myocardial Perfusion Imagining (MPI)?

The practice of MPI with SPECT is prevalent in clinical use. However, it is associated with a widely adopted in clinical practice but is associated with a rather high radiation dose.

In a recent study, 24 patients underwent clinically indicated stress MPI using CZT SPECT with a specific tracer dose. Images were reconstructed at different intervals and analyzed and scored by experienced nuclear medicine physicians. These physicians did not know the patients or scan time. For further information on the methods, results, and conclusion of the study, please follow the link.